The chapel houses two important Byzantine frescos that were rescued from thieves in Europe and restored by the Menil Collection. The building is clad in precast concrete panels over cast-in-place concrete walls. Inside a steel “liner” hangs from the roof. The roof is supported on 8 steel pipe columns and exposed roof beams. There is a gap between the concrete “box” and the steel “lid” that allows in the natural light.

The glass chapel itself is modeled after the original home of the frescos in Cyprus, and is made of flat and curved laminated and sandblasted white annealed glass panels that are held in a "net" of steel rods tensioned between the floor structure and roof. This enables the slender rods to resist any load pattern without buckling. Belleville springs were placed between the rods and the roof structure to ensure continuous tension regardless of roof or floor deflections. The glass panels are held in place by steel clips with specially machined Delrin inserts. Together with the rod frame they function as a composite system for stiffness and strength.